YCR / 2026

01 Data scientist · computational researcher

Charishma
Reddy Yerra.

I build statistical and machine-learning systems for messy, consequential data—from a 4.3M-comment stance-analysis pipeline to Bayesian models for mapping disease variants to candidate genes.

4.3M+

raw comments processed

351,501

curated observations

0.7450

macro-F1

16

cases analyzed

loss surfaceη = 0.08
Gradient descent visualizationContour lines converge toward an optimum, with seven sampled optimization steps.θ0θ1θ2θ3θ4θ5θ6argmin L(θ)model complexity →empirical risk →

∂L/∂θ → 0, but the questions keep moving.

02 f(me)

Evidence in layers. Uncertainty left visible.

My work sits where data pipelines, statistical tests, machine learning, and scientific questions meet. I care about the part before the model—what gets measured, cleaned, compared, and discarded—and the part after it: evaluation, error analysis, and what the result can actually support.

More about my work
pipelinesX_raw → X_curated
modelsargminθ L(θ)
researchP(H | evidence)

03 argmax(project impact)

Selected work

Three research systems that show how I frame problems, combine evidence, and design evaluations.

01Accepted paper · ASONAM 2026

LLM Stance Perception

Women’s Safety Narratives

Measure how stance varies across large-scale social-media discussion of women’s-safety cases in India.

Qwen3.5-9BLoRAMann–Whitney UChi-square
Open case study
02Nearing completion

BayesV2G

Bayesian Variant-to-Gene Prioritization

Prioritize candidate causal genes for cardiometabolic traits from disease-associated variants.

Bayesian inferenceGWAScis-eQTLcis-pQTL
Open case study
03Nearing completion

CoreGene-Bayes

Probabilistic Core-Gene Discovery

Identify candidate core disease genes by modeling convergence of genetic perturbations across molecular pathways.

Bayesian modelingMendelian randomizationMolecular QTLGene networks
Open case study
All six projects

04 Σ experience

From GPU kernels to language models.

Aug 2025 – Present

Graduate Research Capstone

Rochester Institute of Technology

Large-scale discourse and stance analysis across women’s-safety cases in India.

P(stance | narrative)

Aug 2025 – Present

GCCIS Technical Assistant

Rochester Institute of Technology

Academic computing support, software implementation, and resource analysis.

uptime → 1

Jan 2025 – Present

Research Assistant

RIT School of Interactive Games and Media

Quantitative analysis and research communication for instructional-media work.

H₀ ↔ H₁

Jan 2024 – May 2024

Innovation Intern

Forge Innovation and Ventures

User-engagement analysis, KPI reporting, and product-strategy research.

engagement ↑ 25%

Jun 2023 – Aug 2023

High-Performance Computing Intern

National Atmospheric Research Laboratory

GPU-accelerated matrix operations and kernel benchmarking.

O(n³) // GPU
Full experience

05 H₀ vs H₁

Accepted · ASONAM 2026

A short paper built from 4.3 million social-media comments.

The work combines large-scale data curation, nonparametric and categorical tests, LoRA adaptation, held-out evaluation, and high-confidence error auditing.

Research record
accuracy.7447
macro-F1.7450
MCC.6634
n held out3,000

06 X ∈ ℝⁿ

A working feature space

No percentage bars. The tools below are tied to projects, research, or professional work in the attached résumés.

L

Programming

Python · R · SQL · Bash · C

M

Machine learning & NLP

Scikit-learn · XGBoost · PyTorch · LLMs · LoRA / fine-tuning

θ

Bayesian & statistics

Bayesian inference · Hierarchical models · Posterior estimation · Hypothesis testing · Regression

G

Statistical genetics

GWAS · eQTL / pQTL analysis · Colocalization · Variant-to-gene mapping · Mendelian randomization

X

Computational genomics

Molecular QTL integration · Transcriptomics · Spatial gene expression · Gene-set enrichment · GTEx

H

Scientific & HPC

PyMC · ArviZ · SciPy · NumPy · Pandas

Explore the full matrix

07 prior knowledge

Education

Aug 2024 – May 2026

M.S. Data Science

Rochester Institute of Technology

Rochester, NYGPA 3.710 / 4.0

Sep 2020 – May 2024

B.E. Computer Science and Engineering

RMK Engineering College

Chennai, IndiaGPA 3.825 / 4.0

P(reply | context) ↑

Have a hard problem with real data and an honest evaluation?